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Approximately 70% of women with these conditions have a BMI of 30 or higher and often carry metabolic diagnoses such as PCOS or type 2 diabetes

For daily antidepressants at steady state, this typically has no clinically meaningful impact on efficacy

Retatrutide's GLP-1 affinity is the floor of the stack most of the early appetite suppression in the first 4-8 weeks is reportedly GLP-1-mediated